Description

(1R,4R)-4-(Ethoxycarbonyl)Cyclohexanecarboxylic Acid CAS NO 15177-66-9 is a high-purity, stereochemically defined chiral building block. This compound is a critical intermediate in the synthesis of complex pharmaceutical molecules and advanced materials, valued for its rigid cyclohexane backbone and functional handles. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of prostaglandin analogs, antiviral agents, and other bioactive molecules requiring specific stereochemistry.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and plant growth regulators with enhanced efficacy.
• Ligand and Catalyst Preparation: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer Modification: Employed to introduce functional carboxylic acid and ester groups into polymer chains for specialty materials.
• Academic & Industrial R&D: A valuable reagent for medicinal chemistry programs and process chemistry development in laboratory and pilot-scale operations.
• Fine Chemical Production: Integral to multi-step synthetic routes for producing high-value, complex organic compounds.

Basic Information

Item	Detail
Product Name	(1R,4R)-4-(Ethoxycarbonyl)Cyclohexanecarboxylic Acid
CAS No.	15177-66-9
Molecular Formula	C10H16O4
Molecular Weight	200.23 g/mol
Synonyms	(1R,4R)-trans-4-(Ethoxycarbonyl)cyclohexanecarboxylic Acid; trans-4-Carbethoxycyclohexanecarboxylic Acid; (1R,4R)-4-Carbethoxycyclohexanecarboxylic Acid; Ethyl (1R,4R)-4-carboxycyclohexanecarboxylate; 4-(Ethoxycarbonyl)cyclohexanecarboxylic Acid (trans isomer); NSC 163022; trans-4-(Ethoxycarbonyl)cyclohexanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our (1R,4R)-4-(Ethoxycarbonyl)Cyclohexanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and production use. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de (diastereomeric excess)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.