Description

α-Amino-β-Benzoylpropionic Acid is a specialized chiral amino acid derivative with a benzoyl-protected side chain, serving as a critical synthetic intermediate. Its value lies in providing a protected, reactive scaffold for constructing complex peptide mimetics and pharmacologically active molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical and fine chemical industries who require high-purity building blocks for API synthesis and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel peptide-based drugs and enzyme inhibitors.
• Protease Inhibitor Research: Used in the development of renin, HIV protease, and other aspartic protease inhibitors.
• Medicinal Chemistry: A versatile precursor for creating focused libraries of compounds for structure-activity relationship (SAR) studies.
• Peptidomimetic Synthesis: Core structure for developing metabolically stable peptide analogs with enhanced bioavailability.
• Asymmetric Synthesis: Chiral template for the construction of non-natural amino acids and complex organic molecules.
• Bioconjugation: Potential use in linker chemistry for antibody-drug conjugates (ADCs) due to its reactive functional groups.

Basic Information

Product Name	α-Amino-β-Benzoylpropionic Acid
CAS No.	15121-92-3
Molecular Formula	C10H11NO3
Molecular Weight	193.20 g/mol
Synonyms	3-Amino-2-benzoylpropanoic Acid; 3-Amino-2-benzoylpropionic Acid; 2-Benzoyl-3-aminopropanoic Acid; (R,S)-3-Amino-2-benzoylpropionic Acid; DL-3-Amino-2-benzoylpropionic Acid; (±)-3-Amino-2-benzoylpropionic Acid; ABPA; Amino-benzoylpropionic acid
EINECS	Contact for details

Quality Control

Our α-Amino-β-Benzoylpropionic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the stringent requirements for pharmaceutical R&D and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.