Description

R-(-)-2-Butanol is the levorotatory enantiomer of 2-butanol, a chiral secondary alcohol with the CAS registry number 14898-79-4. This optically active compound is a crucial building block in asymmetric synthesis, enabling the production of high-value, enantiomerically pure intermediates. It is essential for research and manufacturing in the pharmaceutical, agrochemical, and fine chemical industries, where precise stereochemistry dictates biological activity and material properties.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: Used in the production of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Asymmetric Catalyst and Ligand Preparation: Serves as a precursor for chiral ligands and catalysts used in enantioselective reactions.
• Agrochemical Research & Development: Employed in the synthesis of enantiomerically pure herbicides, pesticides, and plant growth regulators.
• Flavor and Fragrance Industry: Acts as a chiral starting material for the synthesis of specific stereoisomers that impart distinct sensory profiles.
• Material Science: Utilized in the development of chiral liquid crystals and advanced polymeric materials with specific optical properties.
• Analytical Chemistry: Functions as a chiral resolving agent and a standard for chromatographic method development.

Basic Information

Product Name	R-(-)-2-Butanol
CAS No.	14898-79-4
Molecular Formula	C4H10O
Molecular Weight	74.12 g/mol
Synonyms	(R)-(-)-2-Butanol; (R)-2-Butanol; (R)-sec-Butyl Alcohol; D-(-)-2-Butanol; (R)-Butan-2-ol; (-)-2-Butanol; (2R)-Butan-2-ol; R-(-)-sec-Butanol
EINECS	238-258-1

Quality Control

Our R-(-)-2-Butanol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by GC or HPLC, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and specific impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, keep containers tightly sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability, though it remains stable at controlled room temperature for shorter periods.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Enantiomeric Excess (Chiral GC/HPLC)	≥ 99.0%
Optical Rotation [α]20/D	-13.5° to -14.5° (neat)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.