Description

4-Methoxy-1H-Pyrazole is a versatile heterocyclic building block and a key intermediate in advanced organic synthesis. Its methoxy-substituted pyrazole core is crucial for constructing complex molecules with tailored biological and physical properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and anti-inflammatory drug research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the pyrazole moiety contributes to biological activity.
• Ligand & Catalyst Development: Serves as a precursor for N-heterocyclic carbene (NHC) ligands and other coordination complexes used in catalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers requiring specific heterocyclic architectures.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes and inhibitors to study enzyme function and biological pathways.
• Custom Synthesis & Scale-up: A foundational material for contract research and manufacturing organizations (CROs/CMOs) performing bespoke synthesis for clients.

Basic Information

Product Name	4-Methoxy-1H-Pyrazole
CAS No.	14884-01-6
Molecular Formula	C4H6N2O
Molecular Weight	98.10 g/mol
Synonyms	4-Methoxypyrazole; 1H-Pyrazole, 4-methoxy-; 4-Methoxy-1H-pyrazole; 4-Methoxypyrazole; 4-Methoxy-pyrazole; 4-Methoxy-1H-pyrazole (9CI); NSC 406156; 4-Methoxy-pyrazol; 4-Methoxy-1H-pyrazol
EINECS	Contact for details

Quality Control

Our 4-Methoxy-1H-Pyrazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring GMP-grade intermediates and materials for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.