Description

Methyl Acetimidate Hcl CAS NO 14777-29-8 is a versatile acetimidate ester hydrochloride salt, serving as a key reagent for introducing the acetimidoyl group in organic synthesis. Its primary value lies in its reactivity as an amidine precursor, enabling efficient modifications of amines and other nucleophiles. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of various drug candidates, particularly those containing amidine or guanidine functional groups.
• Bioconjugation & Protein Modification: Used to modify lysine residues or other amine-containing biomolecules for research and diagnostic applications.
• Agrochemical Synthesis: Employed in the production of herbicides, fungicides, and insecticides that require specific amidine structures.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for creating specialty polymers with unique properties.
• Chemical Research & Development: A valuable tool for academic and industrial chemists exploring new reaction pathways and creating novel chemical entities.
• Material Science: Used in surface functionalization and the creation of advanced materials with tailored chemical functionalities.

Basic Information

Product Name	Methyl Acetimidate Hcl
CAS No.	14777-29-8
Molecular Formula	C3H8ClNO
Molecular Weight	109.55 g/mol
Synonyms	Methyl Acetimidate Hydrochloride; Acetimidic Acid Methyl Ester Hydrochloride; Methoxyethanimidamide Hydrochloride; Methyl Acetimidate HCl; Methyl Acetimidate Hydrochloride Salt; Acetamidine, Methyl Ester, Hydrochloride; Methyl Acetimidate Monohydrochloride
EINECS	Contact for details

Quality Control

Our Methyl Acetimidate Hcl is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets high-purity standards suitable for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.