Description

2,2-Dimethyl-1,3-dioxa-2-silacyclohexan-5-ol is a specialized organosilicon compound featuring a cyclic siloxane structure with a pendant hydroxyl group. This unique molecular architecture makes it a valuable protected alcohol synthon and versatile chemical intermediate in advanced organic synthesis. It is primarily utilized by pharmaceutical, agrochemical, and specialty chemical manufacturers for the development of complex molecules where selective protection and functional group manipulation are required.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly where silicon-containing moieties or protected diol functionalities are needed.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, acting as a precursor for silicon-based bioactive compounds.
• Polymer & Material Science: Functions as a monomer or cross-linking agent in the development of specialty silicones, siloxane-based polymers, and hybrid organic-inorganic materials.
• Surface Modification Agent: Employed to modify surface properties of materials, imparting characteristics such as hydrophobicity, lubricity, or specific reactivity.
• Chemical Research & Development: A critical reagent in organic and medicinal chemistry labs for constructing complex molecular architectures and exploring new synthetic pathways.
• Flavor & Fragrance Industry: Potential use as an intermediate in the synthesis of certain aroma chemicals and fragrance ingredients with unique stability profiles.

Basic Information

Product Name	2,2-Dimethyl-1,3-dioxa-2-silacyclohexan-5-ol
CAS No.	14760-14-6
Molecular Formula	C6H12O3Si
Molecular Weight	160.24 g/mol
Synonyms	5-Hydroxy-2,2-dimethyl-1,3-dioxa-2-silacyclohexane; 2,2-Dimethyl-5-hydroxy-1,3-dioxa-2-silacyclohexane; 1,3-Dioxa-2-silacyclohexan-5-ol, 2,2-dimethyl-; (Tetrahydro-5-hydroxy-2H-pyran-2-yloxy)dimethylsilane; Cyclic hydroxymethyl propylenedioxy dimethylsilane; Dihydroxymethylsilyl propylene ketal; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our production of 2,2-Dimethyl-1,3-dioxa-2-silacyclohexan-5-ol adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical specifications. Our quality systems are designed to support cGMP and ISO 9001 standards for traceability and reliability, making this product suitable for demanding industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); ensure containers are kept tightly sealed to prevent degradation from atmospheric humidity. Keep away from strong acids, bases, and oxidizing agents. For long-term storage, consider using an inert atmosphere (nitrogen or argon) to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5% w/w
Refractive Index (n20D)	1.430 - 1.440
Density (20°C)	1.05 - 1.15 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.