Description

(4-Oxo-4H-Quinazolin-3-Yl)-Acetic Acid is a high-purity, versatile quinazolinone derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure makes it a valuable precursor for developing novel compounds with targeted biological and material properties. This intermediate is essential for research and development in the pharmaceutical, agrochemical, and specialty chemical industries, where precise chemical architecture is paramount.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in kinase inhibitor and anticancer agent discovery.
• Agrochemical Synthesis: Used in the creation of advanced active ingredients for crop protection products, leveraging its heterocyclic core.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for electron-transport or host materials in electronic applications due to its rigid, conjugated structure.
• Ligand Synthesis for Catalysis: Employed in the preparation of specialized ligands for metal-catalyzed reactions in fine chemical manufacturing.
• Biochemical Research: Utilized as a scaffold in medicinal chemistry for probing enzyme interactions and structure-activity relationship (SAR) studies.
• Fluorescent Probe Development: Acts as a core structure for synthesizing dyes and molecular probes used in diagnostic and imaging applications.

Basic Information

Product Name	(4-Oxo-4H-Quinazolin-3-Yl)-Acetic Acid
CAS No.	14663-53-7
Molecular Formula	C11H8N2O3
Molecular Weight	216.19 g/mol
Synonyms	3-Quinazolinylacetic acid, 4-oxo-3,4-dihydro-; 2-(4-Oxo-3,4-dihydroquinazolin-3-yl)acetic acid; (4-Oxo-3,4-dihydroquinazolin-3-yl)acetic acid; Quinazolin-3-ylacetic acid, 4-oxo-; 3-Carboxymethyl-4(3H)-quinazolinone; 4-Oxo-3,4-dihydroquinazoline-3-acetic acid
EINECS	Contact for details

Quality Control

Our (4-Oxo-4H-Quinazolin-3-Yl)-Acetic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.