Description

Glyoxylyl Chloride p-Toluenesulfonylhydrazone is a specialized organic synthesis intermediate, primarily valued for its role as a versatile precursor in heterocyclic chemistry. Its core value proposition lies in enabling the efficient construction of complex molecular scaffolds, particularly nitrogen-containing heterocycles, which are pivotal in pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, including potential kinase inhibitors and other biologically active heterocycles.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with novel modes of action.
• Heterocyclic Chemistry: A crucial reagent for constructing pyrazole, isoxazole, and other fused nitrogen-containing ring systems via cyclization reactions.
• Chemical Biology Probes: Serves as a precursor for creating molecular probes used to study enzyme function and biological pathways.
• Material Science Research: Potential intermediate in the development of organic electronic materials and specialty polymers.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic projects.

Basic Information

Product Name	Glyoxylyl Chloride p-Toluenesulfonylhydrazone
CAS No.	14661-69-9
Molecular Formula	C9H9ClN2O3S
Molecular Weight	260.70 g/mol
Synonyms	Glyoxylic Acid Chloride Tosylhydrazone; (Chlorooxoacetyl)-p-toluenesulfonohydrazide; p-Toluenesulfonylhydrazone of Glyoxylyl Chloride; Tosylhydrazone of Glyoxylyl Chloride; 2-Oxo-2-(2-tosylhydrazinyl)acetyl Chloride; α-Chloro-α-oxoacetaldehyde p-Toluenesulfonylhydrazone; Glyoxyloyl Chloride p-Toluenesulfonylhydrazone
EINECS	Contact for details

Quality Control

Every batch of Glyoxylyl Chloride p-Toluenesulfonylhydrazone is produced and tested under a strict quality management system to ensure consistency and reliability for your synthetic workflows. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our standard quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring traceability and documentation for regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.