Description

Benzyloxytrimethylsilane is a versatile organosilicon reagent featuring a benzyl-protected silyl ether group. This compound matters as a critical protecting agent and synthetic intermediate, offering chemists a stable yet cleavable handle for hydroxyl groups in complex molecule assembly. It is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for fine chemical synthesis and process development. Benzyloxytrimethylsilane CAS NO 14642-79-6 is valued for its role in enhancing synthetic efficiency and selectivity.

Application

• Protecting Group Chemistry: Selective protection of primary and secondary alcohols in multi-step organic synthesis.
• Pharmaceutical Intermediates: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators.
• Silicon-Based Materials: Precursor in the sol-gel process for creating hybrid organic-inorganic materials and coatings.
• Polymer Modification: Functionalization agent for introducing silyl ether groups into polymer chains.
• Cross-Coupling Reactions: Reagent in palladium-catalyzed reactions for carbon-silicon bond formation.
• Flavor and Fragrance Industry: Intermediate in the synthesis of specific aromatic compounds.
• Laboratory Research: Standard reagent for method development and exploratory chemistry in R&D settings.

Basic Information

Product Name	Benzyloxytrimethylsilane
CAS No.	14642-79-6
Molecular Formula	C10H16OSi
Molecular Weight	180.32 g/mol
Synonyms	Benzyl Trimethylsilyl Ether; (Benzyloxy)trimethylsilane; Trimethylsilyl Benzyl Ether; O-Benzyltrimethylsilanol; Benzyl O-Trimethylsilyl Ether; TMS-OBn; Silane, benzyloxytrimethyl-; NSC 163083
EINECS	238-678-8

Quality Control

Our Benzyloxytrimethylsilane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to confirm identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its sensitivity to moisture and oxidation, containers must be kept sealed and handled under dry conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Refractive Index (n20D)	1.485 - 1.495
Density (20°C)	0.90 - 0.95 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.