Description

2-Phenyl-2-(Trimethylsilyloxy)Propane is a specialized organosilicon compound that serves as a versatile intermediate in advanced organic synthesis. Its core value lies in its ability to act as a protected ketone equivalent or a silyl enol ether precursor, enabling complex transformations under mild conditions. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity building blocks for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring ketone or enolate chemistry.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where its structural motif is incorporated into the final active molecule.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, fragrances, and advanced materials.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry, including studies on silylation, protection/deprotection strategies, and carbon-carbon bond formation.
• Polymer Chemistry: Potential monomer or modifier in the synthesis of specialty silicon-containing polymers with tailored properties.

Basic Information

Product Name	2-Phenyl-2-(Trimethylsilyloxy)Propane
CAS No.	14629-57-3
Molecular Formula	C12H20OSi
Molecular Weight	208.37 g/mol
Synonyms	2-Phenyl-2-(trimethylsiloxy)propane; 2-Phenyl-2-[(trimethylsilyl)oxy]propane; 1,1-Dimethyl-1-phenyl-2-(trimethylsilyloxy)ethane; Acetophenone trimethylsilyl enol ether; α-(Trimethylsiloxy)isopropylbenzene; TMS enol ether of acetophenone; (2-Phenylpropan-2-yloxy)trimethylsilane
EINECS	Contact for details

Quality Control

Our 2-Phenyl-2-(Trimethylsilyloxy)Propane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to guarantee consistent quality and traceability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The compound is sensitive to moisture; containers should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.