Description

Cyanomethyl p-Toluenesulfonate is a versatile organic sulfonate ester, widely recognized as a key alkylating agent and a valuable synthetic intermediate in organic chemistry. Its primary value lies in its ability to efficiently introduce the cyanomethyl functional group, a crucial precursor to various heterocycles and fine chemicals. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in advanced synthesis and process development.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing nitrile or heterocyclic moieties.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where the cyanomethyl group is incorporated into the final molecule's structure.
• Fine Chemical Production: Serves as a reagent for the alkylation of various nucleophiles (e.g., alcohols, amines, thiols) in the manufacture of dyes, flavors, and fragrances.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the development of specialized polymers and resins.
• Material Science Research: Employed in academic and industrial R&D for creating novel organic materials and liquid crystals.
• Chemical Derivatization: Useful for protecting group chemistry and in multi-step synthetic routes requiring selective functional group transformation.

Basic Information

Item	Detail
Product Name	Cyanomethyl p-Toluenesulfonate
CAS No.	14562-04-0
Molecular Formula	C9H9NO3S
Molecular Weight	211.24 g/mol
Synonyms	p-Toluenesulfonylacetonitrile; Tosylacetonitrile; (p-Tolylsulfonyl)acetonitrile; Cyanomethyl tosylate; 4-Methylbenzenesulfonylacetonitrile; 2-[(4-Methylphenyl)sulfonyl]acetonitrile; TsCH2CN
EINECS	Contact for details

Quality Control

Our Cyanomethyl p-Toluenesulfonate is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and GC for residual solvent analysis, to ensure it meets stringent specifications. Certificates of Analysis (COA) documenting all test results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. This material is moisture-sensitive; ensure containers are kept tightly sealed to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	78 - 82 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.