Description

3-(2-Chloro-3-Thienyl)-5-Methylisoxazole-4-Carboxylic Acid is a high-purity heterocyclic carboxylic acid building block of significant importance in advanced organic synthesis. Its core value lies in its unique molecular architecture, combining a chlorinated thiophene ring with a methylisoxazole carboxylic acid moiety, which is essential for constructing complex pharmacologically active molecules. This compound is primarily needed by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

This versatile chemical intermediate serves as a critical precursor in several high-value synthetic pathways. Its primary applications include:

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the research and development of new generation herbicides, fungicides, and insecticides, leveraging its bioactive core structure.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.
• Chemical Biology & Proteomics: Employed as a specialty reagent for creating molecular probes and activity-based protein profiling (ABPP) tools.
• Academic & Contract Research: Essential for methodological development in organic chemistry and for exploring new reaction mechanisms in industrial and university laboratories.

Basic Information

Product Name	3-(2-Chloro-3-Thienyl)-5-Methylisoxazole-4-Carboxylic Acid
CAS No.	14483-57-9
Molecular Formula	C9H6ClNO3S
Molecular Weight	243.67 g/mol
Synonyms	5-Methyl-3-(2-chloro-3-thienyl)-4-isoxazolecarboxylic acid; 3-(2-Chloro-3-thienyl)-5-methyl-4-isoxazolecarboxylic acid; 4-Isoxazolecarboxylic acid, 3-(2-chloro-3-thienyl)-5-methyl-; 2-Chloro-3-(5-methyl-4-isoxazolecarbonyl)thiophene; 14483-57-9; AI3-52010; CTK8G0138; NSC-403679; SCHEMBL11827579
EINECS	Contact for details

Quality Control

Our production of 3-(2-Chloro-3-Thienyl)-5-Methylisoxazole-4-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure consistency and reliability for your critical synthesis work. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.