Description

Rel-(1R*)-1β*,2α*-Dibromo-1,2-Dihydrobenzocyclobutene is a high-purity, stereospecific brominated benzocyclobutene derivative, serving as a critical chiral building block and reactive intermediate in advanced organic synthesis. This compound matters for its unique strained-ring structure and the reactivity of its vicinal dibromo moiety, enabling precise chemical transformations. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in stereoselective synthesis.
• Agrochemical Research: Used in the creation of new herbicides, fungicides, and insecticides where the benzocyclobutene scaffold imparts unique biological activity.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organocatalysts used in asymmetric catalysis.
• Material Science: A building block for advanced polymers and organic electronic materials due to its rigid, fused-ring structure.
• Academic & Industrial R&D: Employed in methodological studies for ring-opening reactions, cross-coupling, and cycloaddition chemistry.
• Fine Chemical Synthesis: Used in the multi-step production of complex fragrance and flavor compounds.

Basic Information

Item	Details
Product Name	Rel-(1R*)-1β*,2α*-Dibromo-1,2-Dihydrobenzocyclobutene
CAS No.	14420-75-8
Molecular Formula	C8H6Br2
Molecular Weight	261.94 g/mol
Synonyms	(1R*,2S*)-1,2-Dibromo-1,2-dihydrobenzocyclobutene; 1,2-Dibromobenzocyclobutene; rel-(1R,2S)-1,2-Dibromo-1,2-dihydrobenzocyclobutene; Benzocyclobutene, 1,2-dibromo-1,2-dihydro-; 1,2-Dibromodihydrobenzocyclobutene; Dibromobenzocyclobutene; BCB dibromide
EINECS	Contact for details

Quality Control

Our Rel-(1R*)-1β*,2α*-Dibromo-1,2-Dihydrobenzocyclobutene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and stereochemical integrity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.