Description

4',5,7-Triethoxy-3,3',6-Trimethoxyflavone is a high-purity, synthetically derived polymethoxyflavone (PMF) compound, a subclass of flavonoids known for their significant biological activity. This specialized chemical is valued for its role as a key reference standard and active pharmaceutical ingredient (API) intermediate in research and development. It is primarily utilized by the pharmaceutical, nutraceutical, and advanced life science research sectors for applications in metabolic and inflammatory pathway studies.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of flavonoid-based drugs and natural product extracts in HPLC, LC-MS, and NMR methods.
• API Intermediate: Serves as a critical building block in the synthetic pathway for novel therapeutic agents targeting metabolic syndromes.
• Biochemical Research: Employed in in vitro and cell-based assays to study mechanisms related to antioxidant, anti-inflammatory, and enzyme inhibition activities.
• Nutraceutical Development: Investigated as a potential active component in advanced dietary supplements and functional food formulations.
• Cosmeceutical Ingredients: Evaluated for use in premium skincare products for its potential bioactive properties.

Basic Information

Item	Detail
Product Name	4',5,7-Triethoxy-3,3',6-Trimethoxyflavone
CAS No.	14397-67-2
Molecular Formula	C24H28O9
Molecular Weight	460.47 g/mol
Synonyms	3',4',5,6,7-Pentamethoxyflavone (common misnomer); 5,7-Diethoxy-3,3',4',6-tetramethoxyflavone; NSC 407303; Flavone, 4',5,7-triethoxy-3,3',6-trimethoxy-; PMF Derivative; Polyethoxy-methoxyflavone; Triethoxy-trimethoxyflavone
EINECS	Contact for details

Quality Control

Our 4',5,7-Triethoxy-3,3',6-Trimethoxyflavone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.