Description

(2S)-4',5,7-Trihydroxy-6-Methylflavanone CAS NO 14348-16-4 is a high-purity, optically active flavanone derivative, a subclass of flavonoids known for their significant biological activity. This compound is valued for its role as a key intermediate in pharmaceutical research and as a reference standard for analytical and quality control purposes. It is primarily sought by research institutions, pharmaceutical developers, and manufacturers of nutraceuticals and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel therapeutic agents targeting inflammation, oxidative stress, and metabolic disorders.
• Analytical Reference Standard: Used for the identification, purity assessment, and quantification of flavanone compounds in HPLC, LC-MS, and other chromatographic methods.
• Nutraceutical & Cosmetic Research: Investigated for its potential antioxidant, anti-aging, and skin-protective properties in advanced cosmetic formulations and dietary supplements.
• Biochemical Research: Employed in in-vitro and in-vivo studies to explore its mechanisms of action, bioavailability, and pharmacokinetics.
• Fine Chemical Synthesis: Acts as a precursor for the semi-synthesis of other complex natural product analogs and specialty chemicals.

Basic Information

Product Name	(2S)-4',5,7-Trihydroxy-6-Methylflavanone
CAS No.	14348-16-4
Molecular Formula	C₁₆H₁₄O₆
Molecular Weight	302.28 g/mol
Synonyms	(2S)-6-Methylflavan-4',5,7-triol; (S)-4',5,7-Trihydroxy-6-methylflavanone; 6-Methylnaringenin; (2S)-6-Methylnaringenin; (S)-6-Methylnaringenin; 6-Methyl-(2S)-naringenin; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-methyl-(2S)-chroman-4-one; Sophoraflavanone B (stereoisomer)
EINECS	Contact for details

Quality Control

Our (2S)-4',5,7-Trihydroxy-6-Methylflavanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all specifications are provided to ensure full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.