Description

4-Methyl-2-Thiophenecarboxylic Acid is a high-purity organic building block and heterocyclic carboxylic acid derivative essential for advanced chemical synthesis. This compound serves as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and functional materials, where its thiophene core provides unique electronic and structural properties. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating novel compounds and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and development of new generation pesticides and herbicides, leveraging the bioactivity of the thiophene moiety.
• Material Science: Serves as a monomer or functionalizing agent in the production of conductive polymers, organic semiconductors, and advanced organic frameworks (MOFs/COFs).
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalysis, useful in cross-coupling and other transition metal-catalyzed reactions.
• Chemical Research: A versatile building block in academic and industrial R&D for exploring structure-activity relationships (SAR) and synthesizing complex heterocyclic libraries.
• Dye and Pigment Industry: Acts as an intermediate in the synthesis of specialized dyes and pigments that require specific light-absorption or electronic characteristics.

Basic Information

Product Name	4-Methyl-2-Thiophenecarboxylic Acid
CAS No.	14282-78-1
Molecular Formula	C6H6O2S
Molecular Weight	142.18 g/mol
Synonyms	2-Carboxy-4-methylthiophene; 4-Methylthiophene-2-carboxylic Acid; 4-Methyl-2-thiophenecarboxylic acid; 4-Methylthiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid, 4-methyl-; 4-Methyl-2-carboxythiophene; 4-Methylthiophene-α-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 4-Methyl-2-Thiophenecarboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	108 - 112 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.