Description

Allyl Methanethiosulfonate CAS NO 14202-77-8 is a specialized organosulfur compound featuring a reactive methanethiosulfonate group linked to an allyl moiety. This unique structure makes it a valuable alkylating agent and biochemical tool, particularly for the site-specific modification of cysteine residues in proteins and peptides. It is primarily sought by research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in bioconjugation, proteomics, and the synthesis of advanced intermediates.

Application

• Bioconjugation Reagent: For the selective modification of cysteine thiol groups in proteins, antibodies, and peptides to attach probes, drugs, or polymers.
• Proteomics Research: Used in activity-based protein profiling (ABPP) and studies of protein structure, function, and interactions.
• Chemical Biology Tool: Enables the introduction of allyl groups into biomolecules for further functionalization via click chemistry (e.g., thiol-ene reactions).
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of more complex molecules with potential therapeutic applications.
• Polymer Science: Can act as a cross-linking agent or functional monomer in the preparation of specialty polymers with tailored properties.
• Material Surface Modification: Used to create self-assembled monolayers (SAMs) or to functionalize surfaces with reactive allyl groups.

Basic Information

Product Name	Allyl Methanethiosulfonate
CAS No.	14202-77-8
Molecular Formula	C₄H₈O₂S₂
Molecular Weight	152.23 g/mol
Synonyms	Allyl Methanesulfonothioate; Allyl Methyl Thiosulfonate; Methanesulfonothioic Acid Allyl Ester; 2-Propenyl Methanethiosulfonate; AMTS; Allyl Methyl Disulfide Oxide; S-Allyl Methanethiosulfonate
EINECS	Contact for details

Quality Control

Our Allyl Methanethiosulfonate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at temperatures between 2°C and 8°C (refrigerated) to maintain stability and minimize volatility. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.