Description

α-(2-Amino-1-Methylethyl)-4-Methyl-α-(4-Methylphenyl)Benzenemethanol is a specialized chiral amino alcohol building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both benzhydryl and aminoalkyl functionalities, makes it a valuable precursor for constructing complex molecules with high stereochemical control. This compound is primarily utilized by research institutions and pharmaceutical development teams engaged in the creation of novel active pharmaceutical ingredients (APIs), chiral ligands, and other fine chemicals where precise molecular geometry is critical.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) targets.
• Chiral Ligand Precursor: Serves as a starting material for synthesizing sophisticated ligands used in asymmetric catalysis to produce enantiomerically pure compounds.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex organic molecules for agrochemicals and specialty materials.
• Academic & Industrial Research: Used in methodological studies and process chemistry development for exploring new synthetic pathways.

Basic Information

Product Name	α-(2-Amino-1-Methylethyl)-4-Methyl-α-(4-Methylphenyl)Benzenemethanol
CAS No.	14185-12-7
Molecular Formula	C19H25NO
Molecular Weight	283.41 g/mol
Synonyms	α-(2-Amino-1-methylethyl)-4-methyl-α-(4-methylphenyl)benzenemethanol; 1-(4-Methylphenyl)-1-[4-methylphenyl]-2-(1-aminoethyl)ethanol; Benzenemethanol, α-(2-amino-1-methylethyl)-4-methyl-α-(4-methylphenyl)-; (RS)-α-(2-Amino-1-methylethyl)-4-methyl-α-(4-methylphenyl)benzenemethanol; 2-[Hydroxy(4-methylphenyl)methyl]-1-(4-methylphenyl)propan-1-amine
EINECS	Contact for details

Quality Control

Our production of α-(2-Amino-1-Methylethyl)-4-Methyl-α-(4-Methylphenyl)Benzenemethanol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as chiral purity, chemical assay, and impurity profiles. Our quality systems are designed to support cGMP compliance for pharmaceutical development, and we welcome audits and specific quality agreements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (or as specified)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.