Description

Frangulin B CAS NO 14101-04-3 is a naturally occurring anthraquinone glycoside, specifically a rhamnoside of frangula emodin, known for its distinctive biochemical properties. This compound is of significant commercial interest due to its role as a key marker and active component in botanical extracts and pharmaceutical intermediates. It is primarily sought by manufacturers in the pharmaceutical, nutraceutical, and botanical reference standard industries for research, quality control, and product development.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified reference material (CRM) for the identification and quantification of active constituents in herbal drug preparations and finished products.
• Botanical Extract Standardization: Serves as a critical marker compound for the quality control and standardization of extracts derived from Rhamnus species (e.g., Frangula bark) and other anthraquinone-containing botanicals.
• Biochemical Research: Employed in pharmacological and metabolic studies to investigate the properties of anthraquinone glycosides, including potential laxative effects and other biological activities.
• Nutraceutical Ingredient: Utilized as a characterized active ingredient in the formulation of specialized dietary supplements where standardized anthraquinone content is required.
• Analytical Chemistry: Acts as an analytical standard in methods development and validation for techniques like HPLC, UPLC, and LC-MS in quality assurance laboratories.

Basic Information

Product Name	Frangulin B
CAS No.	14101-04-3
Molecular Formula	C21H20O9
Molecular Weight	416.38 g/mol
Synonyms	Frangulin B; Emodin 6-O-α-L-rhamnopyranoside; 6-O-(α-L-Rhamnopyranosyl)emodin; 1,8-Dihydroxy-3-methyl-6-(α-L-rhamnopyranosyloxy)anthraquinone; Franguloside; NSC 407303; Glucofrangulin B (common name for related compound, often used in search)
EINECS	Contact for details

Quality Control

Our Frangulin B is produced and handled under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR) and purity determination by HPLC, to ensure it meets the high standards required for reference materials and pharmaceutical intermediates. A detailed Certificate of Analysis (COA) providing batch-specific data is supplied with every order.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive (store away from light) as indicated by its chemical properties.

Specification

Item	Specification
Appearance	Yellow to orange-yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.