Description

Tetrahydro-4-Hydroxy-6-Isopropyl-5,5-Dimethyl-1H-Pyrimidin-2-One is a high-purity, functionalized pyrimidinone derivative with significant synthetic utility. This compound serves as a versatile advanced pharmaceutical intermediate and a key building block in organic synthesis. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and fine chemical industries for developing novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used as a key building block for developing new-generation herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and complex organic compounds requiring a functionalized heterocyclic core.
• Research & Development (R&D): Serves as a standard or starting material in academic and industrial research for method development and exploring new chemical spaces.
• Ligand and Catalyst Development: Its structure makes it suitable for creating novel ligands for metal catalysis and organocatalysts.

Basic Information

Product Name	Tetrahydro-4-Hydroxy-6-Isopropyl-5,5-Dimethyl-1H-Pyrimidin-2-One
CAS No.	14068-64-5
Molecular Formula	C9H16N2O2
Molecular Weight	184.24 g/mol
Synonyms	4-Hydroxy-6-isopropyl-5,5-dimethyl-1,4,5,6-tetrahydropyrimidin-2(3H)-one; 6-Isopropyl-5,5-dimethyl-1,4,5,6-tetrahydropyrimidine-2,4-diol; Dihydroisocytosine derivative; 2,4(1H,3H)-Pyrimidinedione, tetrahydro-4-hydroxy-6-(1-methylethyl)-5,5-dimethyl-; 14068-64-5; 4-Hydroxy-6-isopropyl-5,5-dimethyl-tetrahydropyrimidin-2-one
EINECS	Contact for details

Quality Control

Our Tetrahydro-4-Hydroxy-6-Isopropyl-5,5-Dimethyl-1H-Pyrimidin-2-One is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity, consistency, and traceability. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We can support development projects with material meeting research-grade to cGMP standards as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. The product may be hygroscopic; handle in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.