Description

But-3-Yn-1-Amine is a versatile alkyne-containing primary amine, serving as a crucial building block in advanced organic synthesis. Its unique structure, featuring a terminal alkyne and a primary amine group, makes it an invaluable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for applications in medicinal chemistry and polymer development.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring alkyne-amine linkages or as a component in click chemistry reactions.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators that incorporate acetylene functionalities.
• Material Science & Polymer Chemistry: Serves as a monomer or cross-linking agent for creating specialty polymers, dendrimers, and functionalized surfaces with tailored properties.
• Chemical Biology & Bioconjugation: Employed in probe and linker synthesis for labeling biomolecules (proteins, nucleic acids) via copper-catalyzed azide-alkyne cycloaddition (CuAAC).
• Ligand & Catalyst Development: Acts as a starting material for synthesizing novel nitrogen-containing ligands used in homogeneous catalysis.
• Organic Synthesis Building Block: Fundamental reagent for constructing heterocycles (like pyrroles, pyridines) and other nitrogen-containing compounds through various cyclization and coupling reactions.

Basic Information

Product Name	But-3-Yn-1-Amine
CAS No.	14044-63-4
Molecular Formula	C4H7N
Molecular Weight	69.11 g/mol
Synonyms	3-Butyn-1-amine; 4-Aminobut-1-yne; 3-Butynylamine; But-3-ynylamine; 1-Amino-3-butyne; 4-Amino-1-butyne; 3-Butyne-1-amine; HC≡CCH2CH2NH2
EINECS	237-861-6

Quality Control

Our But-3-Yn-1-Amine is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile and alkaline nature, it should be kept under an inert atmosphere (e.g., nitrogen or argon) to minimize degradation and moisture absorption. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.