Description

L-3,5-Dichlorophenylalanine is a non-natural, halogenated derivative of the essential amino acid L-phenylalanine. This chiral compound serves as a critical synthetic intermediate and building block in advanced pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and plant growth regulators that incorporate halogenated phenylalanine motifs.
• Peptide Chemistry: Incorporated into custom peptides and peptidomimetics to study structure-activity relationships (SAR) and enhance metabolic stability or binding affinity.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies and as a probe in metabolic pathway analysis.
• Asymmetric Synthesis: Utilized as a starting material or resolving agent in the development of asymmetric catalytic processes and chiral pool syntheses.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	L-3,5-Dichlorophenylalanine
CAS No.	13990-04-0
Molecular Formula	C9H9Cl2NO2
Molecular Weight	234.08 g/mol
Synonyms	(S)-2-Amino-3-(3,5-dichlorophenyl)propanoic acid; L-(3,5-Dichloro)phenylalanine; H-3,5-DiCl-Phe-OH; (S)-3,5-Dichlorophenylalanine; 3,5-Dichloro-L-phenylalanine; 3,5-DCP; 3,5-Dichloro-DL-phenylalanine (racemic mixture); 3,5-Dichloro-α-aminohydrocinnamic acid
EINECS	Contact for details

Quality Control

Our L-3,5-Dichlorophenylalanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets exacting standards for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-Isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.