Description

Embramine Hydrochloride is a pharmaceutical-grade active pharmaceutical ingredient (API) belonging to the ethanolamine class of antihistamines. This compound is valued for its potent H1-receptor antagonist properties, making it a critical component in the formulation of anti-allergic and anti-emetic medications. It is primarily utilized by pharmaceutical manufacturers and research institutions developing treatments for allergic conditions, motion sickness, and related disorders.

Application

• Pharmaceutical API: Primary active ingredient in prescription and over-the-counter anti-allergy medications.
• Antihistamine Formulations: Used in tablets, syrups, and injectables for the symptomatic relief of hay fever, urticaria, and other allergic reactions.
• Anti-emetic Preparations: Key component in drugs designed to prevent and treat nausea and vomiting, including motion sickness.
• Veterinary Medicine: Employed in animal health products for managing allergic responses in livestock and companion animals.
• Biochemical Research: Serves as a reference standard and tool compound in pharmacological studies targeting histamine pathways.
• Intermediate Synthesis: Used as a chemical building block for the synthesis of more complex therapeutic agents.

Basic Information

Product Name	Embramine Hydrochloride
CAS No.	13977-28-1
Molecular Formula	C20H28N2O • HCl
Molecular Weight	348.91 g/mol
Synonyms	Embramine HCl; Mebryl; Bromadryl; 2-[(4-Bromophenyl)-phenylmethoxy]-N,N-dimethylethanamine Hydrochloride; 1-(p-Bromo-α-phenylbenzyloxy)-N,N-dimethylethylamine Hydrochloride; NSC 113986; Diphenhydramine Bromo Analog Hydrochloride
EINECS	Contact for details

Quality Control

Our Embramine Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification, assay, and impurity profiling via HPLC, to ensure it meets high-purity pharmacopeial standards. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.