Description

4-(Trifluoromethoxy)Phenylhydrazine Hydrochloride is a specialized aromatic hydrazine derivative, primarily valued as a high-purity synthetic intermediate in advanced chemical synthesis. Its core value proposition lies in enabling the precise construction of complex molecular architectures, particularly those requiring the trifluoromethoxy pharmacophore. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it serves as a critical building block for active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides that leverage the trifluoromethoxy group for enhanced bioactivity and environmental stability.
• Liquid Crystal & OLED Material Research: Used in the development of novel organic electronic materials and liquid crystal compounds for display technologies.
• Dyestuff & Pigment Chemistry: Intermediate for synthesizing specialized dyes and pigments with unique color fastness and chemical resistance properties.
• Cross-coupling & Cyclization Reactions: Versatile reagent in palladium-catalyzed cross-coupling and heterocyclic ring-forming reactions to create complex nitrogen-containing scaffolds.
• Chemical Research & Development: Fundamental reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	4-(Trifluoromethoxy)Phenylhydrazine Hydrochloride
CAS No.	13957-54-5
Molecular Formula	C7H8F3N2O·HCl
Molecular Weight	232.61 g/mol
Synonyms	4-(Trifluoromethoxy)phenylhydrazine hydrochloride; 1-[4-(Trifluoromethoxy)phenyl]hydrazine hydrochloride; p-(Trifluoromethoxy)phenylhydrazine hydrochloride; 4-(Trifluoromethoxyl)phenylhydrazine HCl; α,α,α-Trifluoro-p-anisidine-4-hydrozine hydrochloride; (4-Trifluoromethoxyphenyl)hydrazine hydrochloride; 4-(Trifluoromethoxy)benzenamine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethoxy)Phenylhydrazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) with full traceability are provided for every shipment, and we support compliance with relevant regulatory frameworks for our global customer base.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.