Description

Tetramethyluronium Chloride is a versatile quaternary ammonium salt widely used as a coupling reagent in organic synthesis. Its primary value lies in its effectiveness in facilitating peptide bond formation and other condensation reactions, offering high yields and minimal racemization. This compound is essential for research and production in the pharmaceutical, biotechnology, and fine chemical industries, where precise and efficient synthesis is critical.

Application

• As a coupling reagent in solid-phase and solution-phase peptide synthesis.
• For the synthesis of amides, esters, and other carboxylic acid derivatives in medicinal chemistry.
• Used in the preparation of active pharmaceutical ingredients (APIs) and complex organic molecules.
• As a reagent in oligonucleotide synthesis and other bioconjugation techniques.
• Employed in academic and industrial research laboratories for method development and scale-up processes.
• Facilitates the production of specialty polymers and advanced materials.

Basic Information

Product Name	Tetramethyluronium Chloride
CAS No.	13829-06-6
Molecular Formula	C5H13ClN2O
Molecular Weight	152.62 g/mol
Synonyms	N,N,N',N'-Tetramethyluronium Chloride; Tetramethyl-O-uronium Chloride; TMC; O-(N,N,N',N'-Tetramethyluronium) Chloride; 1,1,3,3-Tetramethyl-2-oxo-uronium Chloride; Chlorotetramethyluronium; Uronium, tetramethyl-, chloride; Tetramethyluronium Chloride (TMC)
EINECS	Contact for details

Quality Control

Our Tetramethyluronium Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for synthetic reagents. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.