Description

1,5-Dichloro-3-Fluoro-2-(4-Nitrophenoxy)Benzene is a high-purity, multi-functional halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring chloro, fluoro, and nitrophenoxy substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders and infectious diseases.
• Agrochemical Synthesis: Serves as a precursor in the development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated aromatic core.
• Material Science Research: Used in the creation of specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing substituents.
• Dye & Pigment Intermediate: Employed in the synthesis of complex, high-performance dyes and pigments where halogen and nitro groups influence color fastness and spectral properties.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to form complex biaryl and heteroaryl structures.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D exploring new reaction methodologies and constructing molecular libraries.

Basic Information

Product Name	1,5-Dichloro-3-Fluoro-2-(4-Nitrophenoxy)Benzene
CAS No.	13738-63-1
Molecular Formula	C12H6Cl2FNO3
Molecular Weight	302.09 g/mol
Synonyms	2,4-Dichloro-6-fluoro-3-(4-nitrophenoxy)benzene; 3-(4-Nitrophenoxy)-2,4-dichloro-1-fluorobenzene; Benzene, 1,5-dichloro-3-fluoro-2-(4-nitrophenoxy)-; 1-Fluoro-2,4-dichloro-5-(4-nitrophenoxy)benzene; 4-Nitrophenyl 2,4-dichloro-6-fluorophenyl ether
EINECS	Contact for details

Quality Control

Our 1,5-Dichloro-3-Fluoro-2-(4-Nitrophenoxy)Benzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound should be handled in accordance with good laboratory practices, considering its potential sensitivity to moisture and light over extended periods.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.