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2-Methyl-6-(Trimethylsilyl)Pyridine CAS NO 13737-10-5


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CAS No.:13737-10-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Methyl-6-(Trimethylsilyl)Pyridine is a versatile organosilicon-substituted pyridine derivative, valued for its unique steric and electronic properties. This compound serves as a crucial building block and protecting group reagent in advanced synthetic chemistry, particularly for the development of pharmaceuticals and functional materials. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries.

Application

  • Pharmaceutical Intermediate: Key synthon in the synthesis of complex drug molecules, especially those requiring sterically hindered or silicon-protected nitrogen functionalities.
  • Ligand Precursor: Used in the preparation of specialized ligands for catalysis, including those in cross-coupling and polymerization reactions.
  • Material Science: Building block for creating silicon-containing polymers, liquid crystals, and other advanced organic electronic materials.
  • Agrochemical Synthesis: Intermediate in the production of novel pesticides and herbicides where the trimethylsilyl group modifies biological activity.
  • Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and organometallic chemistry.
  • Protecting Group Chemistry: The trimethylsilyl group can act as a protecting group for the pyridine nitrogen, enabling selective reactions at other sites on the molecule.

Basic Information

Product Name 2-Methyl-6-(Trimethylsilyl)Pyridine
CAS No. 13737-10-5
Molecular Formula C9H15NSi
Molecular Weight 165.31 g/mol
Synonyms 6-(Trimethylsilyl)-2-picoline; 2-Picoline, 6-(trimethylsilyl)-; 2-Methyl-6-(trimethylsilyl)pyridine; 2-Methyl-6-trimethylsilylpyridine; 6-Trimethylsilyl-2-methylpyridine; 2-Methyl-6-(trimethylsilyl)azine; (6-Methylpyridin-2-yl)trimethylsilane
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Quality Control

Our 2-Methyl-6-(Trimethylsilyl)Pyridine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Purity (GC/HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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