Description

(-)-3,4-Dihydroxy-2-(3,4-Dihydroxyphenyl)-5-(4-Hydroxyphenyl)-2-Cyclopenten-1-One is a specialized polyphenolic cyclopentenone derivative of significant interest in advanced organic synthesis and life science research. This compound matters for its complex stereochemistry and multiple phenolic hydroxyl groups, which serve as key building blocks for synthesizing novel bioactive molecules and natural product analogs. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents or high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor for the synthesis of complex drug candidates, particularly those targeting neurological or inflammatory pathways.
• Natural Product Synthesis: Used as a key scaffold in the total or semi-synthesis of naturally occurring polyphenols and lignans with potential biological activity.
• Biochemical Research: Employed as a reference standard or probe in studies investigating antioxidant mechanisms, enzyme inhibition, or cellular signaling pathways.
• Agrochemical Development: Acts as a starting material for creating novel plant growth regulators or environmentally benign pesticide derivatives.
• Material Science Precursor: Utilized in the development of advanced polymeric materials or functional coatings where specific phenolic interactions are required.
• Catalysis & Ligand Design: Provides a versatile framework for designing novel chiral ligands used in asymmetric catalysis for manufacturing high-purity enantiomers.

Basic Information

Product Name	(-)-3,4-Dihydroxy-2-(3,4-Dihydroxyphenyl)-5-(4-Hydroxyphenyl)-2-Cyclopenten-1-One
CAS No.	13677-78-6
Molecular Formula	C17H14O5
Molecular Weight	298.29 g/mol
Synonyms	(-)-3,4-Dihydroxy-2-(3,4-dihydroxyphenyl)-5-(4-hydroxyphenyl)cyclopent-2-en-1-one; 2-Cyclopenten-1-one, 3,4-dihydroxy-2-(3,4-dihydroxyphenyl)-5-(4-hydroxyphenyl)-, (-)-; (2R,3S,4S,5R)-2,3,4,5-Tetrahydroxy-2,3,4,5-tetraphenylcyclopentanone (related structural isomer); Polyphenolic Cyclopentenone Derivative; NSC 407347; LCCP Derivative; Chiral Cyclopentenone Diol
EINECS	Contact for details

Quality Control

Our (-)-3,4-Dihydroxy-2-(3,4-Dihydroxyphenyl)-5-(4-Hydroxyphenyl)-2-Cyclopenten-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure identity, strength, and composition. Certificates of Analysis (COA) detailing specific results for assay, chiral purity, and related substances are provided and can be tailored to meet client-specific monograph requirements or internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity to oxidation and light, prolonged exposure to air or ambient light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.