Description

3-Bromo-4-Chlorophenol is a halogenated phenolic compound that serves as a versatile and critical building block in advanced organic synthesis. Its value lies in its ability to introduce both bromine and chlorine substituents onto a phenolic core, enabling precise structural modifications. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity, functionalized aromatic compounds for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring halogenated aromatic motifs for bioactivity.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and pesticides where the phenolic structure contributes to the compound's efficacy.
• Material Science: Serves as a monomer or functionalizing agent in the development of specialty polymers, resins, and liquid crystals.
• Dye and Pigment Manufacturing: Acts as an intermediate for creating halogenated dyes and organic pigments.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Cross-Coupling Reactions: Utilized in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) due to the presence of halogen atoms suitable for metal-halogen exchange.

Basic Information

Product Name	3-Bromo-4-Chlorophenol
CAS No.	13659-24-0
Molecular Formula	C6H4BrClO
Molecular Weight	207.45 g/mol
Synonyms	4-Chloro-3-bromophenol; 3-Bromo-4-chloro-1-hydroxybenzene; Phenol, 3-bromo-4-chloro-; 1-Hydroxy-3-bromo-4-chlorobenzene; 3-Bromo-4-chlorophenol (primary); 4-Chloro-3-bromo-phenol; 3-Br-4-Cl-Phenol
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Chlorophenol is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, and NMR for comprehensive characterization and impurity profiling. Certificates of Analysis (COA) detailing purity, identity, and specific tests are provided with each shipment and are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.