Description

3-Hydroxyisoxazole-5-Carboxylic Acid is a heterocyclic carboxylic acid derivative that serves as a versatile and high-value synthetic building block in advanced organic chemistry. Its unique isoxazole core functionalized with both a hydroxyl and a carboxylic acid group makes it a critical intermediate for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Ligand and Chelating Agent: Serves as a building block for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the development of advanced polymers and functional materials with specific optical or electronic properties.
• Bioconjugation and Probe Development: Useful in medicinal chemistry for creating fluorescent probes or bioconjugates for diagnostic applications.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in heterocyclic and synthetic organic chemistry.

Basic Information

Product Name	3-Hydroxyisoxazole-5-Carboxylic Acid
CAS No.	13626-60-3
Molecular Formula	C4H3NO4
Molecular Weight	129.07 g/mol
Synonyms	5-Isoxazolecarboxylic acid, 3-hydroxy-; 3-Hydroxy-1,2-oxazole-5-carboxylic acid; 3-Hydroxyisoxazole-5-carboxylic acid; 5-Carboxy-3-hydroxyisoxazole; 3-Hydroxy-5-carboxyisoxazole; Isoxazol-3-ol-5-carboxylic acid; 3-Hydroxy-5-isoxazolecarboxylic acid
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Production of 3-Hydroxyisoxazole-5-Carboxylic Acid is monitored through in-process checks and final release testing against established internal specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each batch to ensure traceability and compliance for your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.