Description

8-Iodo-1-naphthoic acid is a halogenated naphthoic acid derivative that serves as a versatile and valuable synthetic intermediate in advanced organic chemistry. Its core value lies in the strategic reactivity of the iodine substituent, enabling efficient cross-coupling reactions for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to develop novel active ingredients and functional organic materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the production of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The iodine atom is pivotal in metal-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings for carbon-carbon bond formation.
• Ligand and Catalyst Development: Utilized to create complex organic ligands for catalysis and coordination chemistry.
• Chemical Research & Development: A fundamental reagent in academic and industrial R&D labs for exploring new synthetic pathways.

Basic Information

Product Name	8-Iodo-1-naphthoic Acid
CAS No.	13577-19-0
Molecular Formula	C11H7IO2
Molecular Weight	298.08 g/mol
Synonyms	1-Naphthoic acid, 8-iodo-; 8-Iodonaphthalene-1-carboxylic Acid; 8-Iodo-1-naphthalenecarboxylic Acid; 8-Iodonaphthalene-1-carboxylic Acid; 8-Iodo-1-naphthoic acid; 13577-19-0; 8-Iodo-1-naphthoic acid (CAS 13577-19-0)
EINECS	Contact for details

Quality Control

Our 8-Iodo-1-naphthoic acid is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, NMR, and mass spectrometry, for comprehensive characterization and impurity profiling. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming specifications for identity, purity, and related substances. Our quality system supports compliance with cGMP and ISO standards for research and commercial-scale applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.