Description

4-Chloro-2-Iodobenzoic Acid is a halogenated benzoic acid derivative that serves as a versatile and valuable building block in advanced organic synthesis. Its unique structure, featuring both chloro and iodo substituents, makes it a critical intermediate for constructing complex molecules with precise electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research for drug discovery.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging its halogenated aromatic core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and polymers requiring specific halogenated motifs.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions, such as Suzuki and Sonogashira couplings.
• Chemical Derivatization: The carboxylic acid group allows for further functionalization to amides, esters, and other derivatives for library synthesis.

Basic Information

Product Name	4-Chloro-2-Iodobenzoic Acid
CAS No.	13421-13-1
Molecular Formula	C7H4ClIO2
Molecular Weight	282.46 g/mol
Synonyms	2-Iodo-4-chlorobenzoic acid; Benzoic acid, 4-chloro-2-iodo-; 4-Chloro-2-iodobenzoic acid; 4-Chloro-2-iodobenzenecarboxylic acid; 2-Iodo-4-chlorobenzenecarboxylic acid; 4-Chloro-o-iodobenzoic acid; 4-Chloro-2-iodo-benzoic acid
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Iodobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We are committed to meeting the stringent requirements of research and development as well as cGMP standards for advanced intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and reducing agents. The compound is light-sensitive; store away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.