Description

2-Trimethylsilyl-1,3-dithiane is a versatile organosilicon-protected dithiane reagent, primarily used as a synthetic building block in advanced organic synthesis. Its core value lies in its ability to act as a masked acyl anion equivalent, enabling the controlled introduction of carbonyl functionality under mild conditions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries engaged in complex molecule construction.

Application

• Pharmaceutical Intermediates: Key synthon for the synthesis of complex drug molecules, particularly in constructing chiral centers and heterocyclic systems.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides requiring specific stereochemistry.
• Material Science Precursors: Serves as a precursor for functionalized materials and ligands in catalysis.
• Natural Product Synthesis: Employed in the total synthesis of natural products where the dithiane moiety is used for chain elongation and functional group manipulation.
• Asymmetric Synthesis: Utilized in stereoselective reactions to create enantiomerically pure compounds.
• Process Chemistry: Valued for its stability and reactivity profile in scalable manufacturing processes for fine chemicals.

Basic Information

Product Name	2-Trimethylsilyl-1,3-dithiane
CAS No.	13411-42-2
Molecular Formula	C7H16S2Si
Molecular Weight	192.41 g/mol
Synonyms	1,3-Dithian-2-yltrimethylsilane; Trimethyl(1,3-dithian-2-yl)silane; 2-(Trimethylsilyl)-1,3-dithiane; 2-TMS-1,3-dithiane; (1,3-Dithian-2-yl)trimethylsilane; Silane, trimethyl(1,3-dithian-2-yl)-; 2-Trimethylsilyl-1,3-dithian
EINECS	Contact for details

Quality Control

Our 2-Trimethylsilyl-1,3-dithiane is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.