Description

4-Amino-1-Cyclohexene-1-Carboxylic Acid is a versatile, functionalized cyclohexene derivative that serves as a key chiral building block and intermediate in advanced organic synthesis. Its unique structure, featuring both an amino group and a carboxylic acid on a cyclohexene ring, makes it invaluable for constructing complex molecular architectures with precise stereochemistry. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries, where it is used to develop novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and plant growth regulators with specific stereochemical requirements.
• Ligand and Catalyst Precursor: Serves as a starting material for the preparation of chiral ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Peptidomimetic and Bioisostere Research: The constrained cyclohexene scaffold is utilized to design and synthesize conformationally restricted peptide analogs and bioisosteres.
• Fine Chemical and Specialty Material Production: Employed in the manufacture of high-value, performance chemicals requiring specific stereocenters and functional groups.
• Academic and R&D Laboratories: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Item	Details
Product Name	4-Amino-1-Cyclohexene-1-Carboxylic Acid
CAS No.	13372-08-2
Molecular Formula	C7H11NO2
Molecular Weight	141.17 g/mol
Synonyms	4-Amino-1-cyclohexene-1-carboxylic acid; 1-Cyclohexene-1-carboxylic acid, 4-amino-; 4-Aminocyclohex-1-ene-1-carboxylic acid; (4-Aminocyclohex-1-en-1-yl)formic acid; 4-Amino-1-cyclohexenecarboxylic acid; 4-Amino-cyclohex-1-enecarboxylic acid; 4-Amino-1-cyclohexene carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-Amino-1-Cyclohexene-1-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment. We support custom purity requirements and can provide material compliant with cGMP standards for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged operations to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.