Description

2-Chlorotetrahydrofuran is a versatile chlorinated heterocyclic compound and a valuable building block in organic synthesis. Its primary value lies in its dual functionality, serving as both a reactive chlorinated intermediate and a protected form of 4-chlorobutan-1-ol, enabling diverse chemical transformations. This chemical is essential for research laboratories and industrial-scale manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors who require high-purity intermediates for complex molecule assembly.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing tetrahydrofuran or pyrrolidine ring systems.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents where its chlorinated ring structure is incorporated into the final molecule.
• Polymer Chemistry: Acts as a monomer or modifying agent in the creation of specialty polymers and resins, imparting specific chemical resistance or physical properties.
• Organic Synthesis Reagent: Employed in nucleophilic substitution reactions, ring-opening polymerizations, and as a starting material for preparing Grignard reagents and other organometallic compounds.
• Solvent and Reaction Medium: Functions as a polar aprotic solvent for specific organic reactions where its properties are advantageous over more common alternatives.
• Chemical Research: A fundamental reagent in academic and industrial R&D for exploring new synthetic methodologies and constructing complex molecular architectures.

Basic Information

Product Name	2-Chlorotetrahydrofuran
CAS No.	13369-70-5
Molecular Formula	C4H7ClO
Molecular Weight	106.55 g/mol
Synonyms	2-Chlorooxolane; 2-Chloro-tetrahydrofuran; α-Chlorotetrahydrofuran; Tetrahydro-2-chlorofuran; 2-Chlorotetrahydrofuran; 2-Chlorooxacyclopentane; 2-Chlorotetrahydrofuran (stabilized); 2-Chlorooxolane (IUPAC)
EINECS	Contact for details

Quality Control

Our 2-Chlorotetrahydrofuran is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment supports applications requiring reliable and reproducible performance in sensitive syntheses.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile and light-sensitive nature, it is recommended to store at temperatures between 2°C and 8°C for extended stability. Keep container tightly sealed when not in use to prevent evaporation and moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.435 - 1.445
Density (20°C)	1.08 - 1.12 g/mL
Boiling Point	118 - 122 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.