Description

3-Isopropylcyclobutanecarboxylic Acid is a specialized cyclobutane derivative carboxylic acid, serving as a versatile chiral building block and intermediate in advanced organic synthesis. Its unique sterically constrained cyclobutane ring fused with an isopropyl group makes it valuable for constructing complex molecular architectures with specific spatial orientations. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Building block for creating advanced herbicides and fungicides with enhanced stereoselectivity and biological activity.
• Ligand and Catalyst Development: Precursor for synthesizing chiral ligands used in asymmetric catalysis, such as phosphines and N-heterocyclic carbenes (NHCs).
• Material Science Research: Monomer or modifier for developing polymers with unique thermal and mechanical properties derived from the rigid cyclobutane structure.
• Flavor and Fragrance Chemistry: Intermediate for the production of high-value aroma chemicals and synthetic musk compounds.
• Academic and R&D Laboratories: Used in methodological studies and the exploration of new synthetic routes involving strained ring systems.

Basic Information

Product Name	3-Isopropylcyclobutanecarboxylic Acid
CAS No.	13363-91-2
Molecular Formula	C8H14O2
Molecular Weight	142.20 g/mol
Synonyms	3-(1-Methylethyl)cyclobutanecarboxylic Acid; 3-Isopropylcyclobutane-1-carboxylic Acid; Cyclobutanecarboxylic acid, 3-(1-methylethyl)-; 3-Isopropyl-1-cyclobutanecarboxylic Acid; 3-Propan-2-ylcyclobutanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our production of 3-Isopropylcyclobutanecarboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic (HPLC, GC) and spectroscopic (NMR, IR) techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.