Description

2-Hydroxy-2,3-Dihydro-1H-Indene-2-Carboxylic Acid is a versatile indane derivative carboxylic acid that serves as a critical chiral building block and synthetic intermediate in advanced organic synthesis. Its unique fused bicyclic structure provides a rigid scaffold, making it valuable for constructing complex molecules with defined stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key chiral precursor for the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs), enzyme inhibitors, and other bioactive molecules.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Ligand and Catalyst Development: Used to prepare chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Intermediate in the manufacture of dyes, pigments, and advanced polymeric materials.
• Academic & R&D: Serves as a standard and starting material in medicinal chemistry research and process development.
• Material Science: Potential monomer for synthesizing specialty polyesters and polyamides with unique thermal properties.

Basic Information

Product Name	2-Hydroxy-2,3-Dihydro-1H-Indene-2-Carboxylic Acid
CAS No.	13193-24-3
Molecular Formula	C10H10O3
Molecular Weight	178.18 g/mol
Synonyms	2-Hydroxyindane-2-carboxylic Acid; 2-Carboxy-2-hydroxyindane; 2-Hydroxy-2,3-dihydro-1H-indene-2-carboxylic acid; 2-Hydroxyhydrindacarboxylic Acid; (±)-2-Hydroxy-2,3-dihydro-1H-indene-2-carboxylic acid; Indane-2-carboxylic acid, 2-hydroxy-; 2-Hydroxy-2,3-dihydro-1H-indene-2-carboxylic Acid (racemic); 13193-24-3
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-2,3-Dihydro-1H-Indene-2-Carboxylic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay, chiral purity (if applicable), and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Chiral Purity (if applicable)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.