Description

4-Trimethylsilylphenol is a versatile organosilicon intermediate featuring a phenolic hydroxyl group protected by a trimethylsilyl moiety. This compound is valued for its role as a key building block in organic synthesis, particularly in the production of advanced materials and specialty chemicals. It is essential for manufacturers and R&D laboratories in the pharmaceutical, agrochemical, and polymer industries seeking to introduce silyl-protected phenolic functionalities into their molecular architectures.

Application

• Pharmaceutical Intermediates: Serves as a protected phenol precursor in the synthesis of active pharmaceutical ingredients (APIs) and complex drug molecules.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and pesticides where the silyl group aids in selective reactions.
• Polymer & Material Science: Acts as a monomer or modifying agent for creating silicone-modified resins, heat-resistant polymers, and specialty coatings.
• Organic Synthesis Reagent: Functions as a versatile reagent for introducing the trimethylsilyl group, facilitating protection/deprotection strategies and cross-coupling reactions.
• Liquid Crystal & OLED Materials: Employed in the development of advanced electronic and optoelectronic materials due to its stable aromatic-silicon structure.
• Adhesive & Sealant Formulations: Used as an additive to enhance specific properties like adhesion, thermal stability, or moisture resistance in high-performance formulations.

Basic Information

Product Name	4-Trimethylsilylphenol
CAS No.	13132-25-7
Molecular Formula	C9H14OSi
Molecular Weight	166.29 g/mol
Synonyms	p-(Trimethylsilyl)phenol; 4-(Trimethylsilyl)phenol; Phenol, 4-(trimethylsilyl)-; 4-Hydroxyphenyltrimethylsilane; p-Hydroxyphenyltrimethylsilane; TMS-Phenol; 4-TMS-Phenol; 4-Trimethylsilyl-phenol
EINECS	236-076-5

Quality Control

Our 4-Trimethylsilylphenol is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing specific results for purity, appearance, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	88 - 92 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.