Description

n-Carbobenzoxy-L-Phenylalanyl-L-Phenylalanine is a protected dipeptide building block of significant importance in synthetic organic and peptide chemistry. Its core value lies in enabling the controlled synthesis of complex peptide sequences, particularly those containing phenylalanine residues, by providing orthogonal protection for the amine terminus. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who are developing novel peptide-based therapeutics, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the sequential assembly of longer peptide chains in both research and GMP production settings.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) for peptide drugs targeting metabolic disorders, CNS conditions, and oncology.
• Bioconjugation & Probe Development: Serves as a precursor for creating labeled peptides used in imaging, diagnostics, and targeted drug delivery systems.
• Biochemical Research: Employed in studying enzyme-substrate interactions, protease specificity, and peptide structure-activity relationships (SAR).
• Custom Peptide Service: A fundamental raw material for contract research and manufacturing organizations (CROs/CMOs) offering bespoke peptide synthesis.

Basic Information

Product Name	n-Carbobenzoxy-L-Phenylalanyl-L-Phenylalanine
CAS No.	13122-91-3
Molecular Formula	C26H26N2O5
Molecular Weight	446.50 g/mol
Synonyms	Z-L-Phe-L-Phe-OH; Cbz-L-Phe-L-Phe-OH; N-Carbobenzoxy-L-phenylalanyl-L-phenylalanine; Benzyloxycarbonyl-L-phenylalanyl-L-phenylalanine; Z-Phe-Phe-OH; CBZ-Phe-Phe; Nα-Cbz-L-Phenylalanyl-L-phenylalanine; (2S)-2-[[(2S)-2-(phenylmethoxycarbonylamino)-3-phenylpropanoyl]amino]-3-phenylpropanoic acid
EINECS	Contact for details

Quality Control

Our n-Carbobenzoxy-L-Phenylalanyl-L-Phenylalanine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via spectroscopic methods. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with your research or cGMP manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L,L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.