Description

1-Bromo-3-Chloro-5-Iodobenzene is a high-purity, multi-halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique substitution pattern makes it a versatile and valuable intermediate for constructing complex molecular architectures. This compound is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for applications in drug discovery, ligand synthesis, and the development of functional organic materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in cross-coupling reactions like Suzuki, Negishi, and Sonogashira couplings.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides, where the halogen atoms provide handles for further functionalization.
• Material Science: Acts as a building block for creating organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) due to its rigid benzene core and halogen substituents.
• Chemical Research: Employed in academic and industrial R&D as a model substrate for developing new catalytic methodologies and studying reaction mechanisms involving halogenated arenes.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized phosphine or N-heterocyclic carbene (NHC) ligands used in homogeneous catalysis.

Basic Information

Product Name	1-Bromo-3-Chloro-5-Iodobenzene
CAS No.	13101-40-1
Molecular Formula	C6H3BrClI
Molecular Weight	317.35 g/mol
Synonyms	3-Bromo-5-Chloro-1-Iodobenzene; 5-Bromo-1-Chloro-3-Iodobenzene; 1-Bromo-5-Chloro-3-Iodobenzene; 3-Chloro-5-Iodobromobenzene; m-Bromo-m-chloro-m-iodobenzene; Benzene, 1-bromo-3-chloro-5-iodo-; (3-Bromo-5-chlorophenyl) iodide
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Chloro-5-Iodobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee consistent quality and traceability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.