Description

3-Bromo-Tetrahydro-Pyran is a versatile brominated heterocyclic building block of significant importance in advanced organic synthesis. Its reactive bromine atom and stable tetrahydropyran ring make it a key intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for introducing the tetrahydropyran moiety.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its reactivity for structural diversification.
• Ligand and Catalyst Preparation: Acts as a precursor for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.
• Material Science Research: Employed in the development of novel polymers, liquid crystals, and other functional materials where the bromine serves as a handle for further functionalization.
• Chemical Biology Probes: Useful for the synthesis of molecular probes and tags used in biochemical assays and diagnostic research.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global fine chemical market.

Basic Information

Product Name	3-Bromo-Tetrahydro-Pyran
CAS No.	13047-01-3
Molecular Formula	C5H9BrO
Molecular Weight	165.03 g/mol
Synonyms	3-Bromotetrahydropyran; 3-Bromooxane; Tetrahydro-3-bromo-2H-pyran; 3-Bromo-tetrahydro-2H-pyran; 2H-Pyran, 3-bromotetrahydro-; 3-Bromotetrahydro-2H-pyran; Bromotetrahydropyran
EINECS	Contact for details

Quality Control

Our 3-Bromo-Tetrahydro-Pyran is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with global regulatory frameworks, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index	1.480 - 1.490
Density	1.45 - 1.55 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.