Description

Mafenide Acetate is a synthetic antimicrobial agent belonging to the sulfonamide class, recognized for its broad-spectrum activity against gram-positive and gram-negative bacteria. Its primary commercial value lies in its established efficacy as a topical antibacterial agent, particularly for preventing and treating infections in burn wounds. This makes it a critical raw material for pharmaceutical manufacturers specializing in dermatological and wound care products. Global demand is driven by its use in compounding pharmacies and the production of medicated creams and solutions.

Application

• Active Pharmaceutical Ingredient (API) in topical antibacterial creams and ointments for burn wound management.
• Key intermediate in the synthesis of advanced antimicrobial formulations for hospital and clinical use.
• Raw material for compounding pharmacies preparing patient-specific dermatological treatments.
• Research and development of novel antimicrobial agents and combination therapies.
• Manufacturing of medicated wound dressings and gels for infection control.
• Reference standard in analytical laboratories for quality control and pharmaceutical testing.

Basic Information

Product Name	Mafenide Acetate
CAS No.	13009-99-9
Molecular Formula	C7H10N2O2S • C2H4O2
Molecular Weight	246.28 g/mol
Synonyms	4-Aminomethylbenzenesulfonamide acetate; α-Amino-p-toluenesulfonamide acetate; Sulfamylon; Homosulfamine; Marfanil acetate; p-(Aminomethyl)benzenesulfonamide monoacetate; Mafenide acetate salt; Ambamide
EINECS	235-860-8

Quality Control

Our Mafenide Acetate is manufactured under strict quality management systems to ensure it meets the rigorous standards required for pharmaceutical applications. Each batch is tested against comprehensive specifications, including identity, purity, and impurity profiles, using validated analytical methods such as HPLC and titration. A Certificate of Analysis (COA) is provided with every shipment, detailing the results for traceability and regulatory compliance. We support customers requiring material that aligns with pharmacopeial standards (e.g., USP).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be kept under conditions that minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	98.0% - 102.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.