Description

Barium Hydroxyapatite CAS NO 12356-34-2 is a specialized inorganic compound, a barium-substituted derivative of the calcium phosphate mineral hydroxyapatite. This engineered material is valued for its unique combination of bioactivity and enhanced radiopacity, making it a critical component in advanced material science and biomedical applications. It is primarily sought by manufacturers and researchers in the medical device, biomaterials, and specialty ceramics industries for developing next-generation implants and diagnostic materials.

Application

• Biomedical Implants & Bone Cements: As a radiopaque filler and bioactive agent in orthopedic and dental bone void fillers and cements to enable post-operative X-ray monitoring.
• Radiopaque Biomaterial Coatings: For coating metallic implants (e.g., joint replacements, spinal devices) to improve biocompatibility and provide clear imaging contrast.
• Composite Material Reinforcement: Used as a functional filler in polymer composites to enhance mechanical strength, bioactivity, and X-ray visibility for medical applications.
• Chromatography Media: Acts as a substrate in high-performance liquid chromatography (HPLC) for the separation of biomolecules, including proteins and nucleic acids.
• Specialty Ceramics & Catalysts: A precursor material for producing advanced ceramics with specific dielectric or catalytic properties.
• Environmental Remediation: Utilized as an adsorbent for the removal of specific anions or heavy metal ions from wastewater streams.
• Dental Restorative Materials: Incorporated into advanced dental composites and cements to improve radiopacity for caries detection.
• Research & Development: Serves as a model compound in materials science research for studying ion-substitution effects in apatite structures.

Basic Information

Product Name	Barium Hydroxyapatite
CAS No.	12356-34-2
Molecular Formula	Ba5(PO4)3OH or Ca(10-x)Bax(PO4)6(OH)2
Molecular Weight	Contact for details (varies with Ba substitution level)
Synonyms	Barium-substituted Hydroxyapatite; Barium Apatite; Barium Calcium Phosphate Hydroxide; Barium Hydroxylapatite; Barium-Doped Hydroxyapatite; Barium HA; Barium-Containing Apatite; Radiopaque Hydroxyapatite
EINECS	Contact for details

Quality Control

Our Barium Hydroxyapatite is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure consistency in composition, phase purity, particle size distribution, and trace impurity levels. Certificates of Analysis (COA) detailing key parameters such as barium content, Ca/P ratio, crystallinity, and specific surface area are provided with every shipment. We can tailor specifications to meet research-grade or GMP-grade requirements for biomedical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive). Keep the container tightly sealed when not in use to prevent moisture absorption and potential caking. Store away from incompatible substances such as strong acids.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (XRD)	Conforms to Hydroxyapatite structure pattern
Barium (Ba) Content	As specified per grade (e.g., 5-20 mol%)
Calcium/Phosphorus (Ca/P) Molar Ratio	~1.67 (Theoretical for HA)
Assay (as Hydroxyapatite)	≥ 95.0% - 99.9%
Crystallinity (by XRD)	Reported
Particle Size (D50)	Customizable (e.g., 1-50 µm)
Specific Surface Area (BET)	Reported
Loss on Drying	≤ 2.0%
Heavy Metals (as Pb)	≤ 20 ppm
pH (in aqueous suspension)	6.5 - 8.5

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.