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1,1'-Bis(Diphenylphosphino)Ferrocene CAS NO 12150-46-8


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CAS No.:12150-46-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,1'-Bis(Diphenylphosphino)Ferrocene is a highly versatile and widely used organometallic ligand, commonly known as dppf. This compound is prized for its exceptional ability to stabilize transition metal catalysts, significantly enhancing reaction rates and selectivity in complex synthetic processes. It is an essential raw material for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where precise catalytic control is paramount for developing new active ingredients and functional polymers.

Application

  • Homogeneous Catalysis: A premier ligand in cross-coupling reactions (e.g., Suzuki, Negishi, Stille) for C-C and C-X bond formation in pharmaceutical intermediates.
  • Pharmaceutical Synthesis: Critical for the production of complex drug molecules and active pharmaceutical ingredients (APIs) requiring high-purity catalytic steps.
  • Agrochemical Manufacturing: Used in the synthesis of novel pesticides and herbicides where selective catalysis improves yield and reduces waste.
  • Material Science: Employed in the development of conductive polymers, OLED materials, and other advanced organic electronic components.
  • Asymmetric Synthesis: Serves as a chiral ligand precursor for creating enantioselective catalysts used in fine chemical production.
  • Academic & Industrial R&D: A fundamental reagent in chemistry laboratories for method development and exploring new catalytic transformations.

Basic Information

Product Name 1,1'-Bis(Diphenylphosphino)Ferrocene
CAS No. 12150-46-8
Molecular Formula C34H28FeP2
Molecular Weight 554.38 g/mol
Synonyms dppf; 1,1'-Ferrocenediyl-bis(diphenylphosphine); Bis(diphenylphosphino)ferrocene; DPPF; 1,1'-Bis(diphenylphosphanyl)ferrocene; NSC 169155; Ferrocene-1,1'-diylbis(diphenylphosphane); (Ferrocene-1,1'-diyl)bis(diphenylphosphane)
EINECS 235-254-6

Quality Control

Our 1,1'-Bis(Diphenylphosphino)Ferrocene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for all commercial and research quantities.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at room temperature (15-25°C). This compound is easily oxidized and moisture-sensitive; prolonged exposure to air should be avoided to maintain purity and efficacy.

Specification

Item Specification
Appearance Orange to red crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Melting Point 180 - 184 °C
Loss on Drying ≤ 0.5 %
Heavy Metals (as Pb) ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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