Description

2-Methyl-5-Hydroxypentanoic Acid Lactone is a specialized lactone derivative with a unique branched-chain structure. This compound serves as a valuable chiral building block and intermediate in the synthesis of complex organic molecules, offering significant utility in fine chemical and pharmaceutical manufacturing. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fragrance industries for constructing active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of cardiovascular and central nervous system drugs.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its lactone functionality is leveraged for ring-opening reactions.
• Flavor & Fragrance Ingredient: Acts as a precursor for musk-like odorants and complex flavoring agents due to its lactonic character.
• Polymer Chemistry: Serves as a monomer or co-monomer for synthesizing specialized polyesters and biodegradable polymers.
• Organic Synthesis Reagent: Employed in academic and industrial research laboratories for asymmetric synthesis and the construction of heterocyclic compounds.
• Cosmetic Ingredients: Utilized in the synthesis of certain emollients and skin-conditioning agents.

Basic Information

Product Name	2-Methyl-5-Hydroxypentanoic Acid Lactone
CAS No.	10603-03-9
Molecular Formula	C6H10O2
Molecular Weight	114.14 g/mol
Synonyms	5-Hydroxy-2-methylpentanoic acid lactone; 2-Methyl-δ-valerolactone; 2-Methyl-5-hydroxypentanoic acid δ-lactone; 2-Methyltetrahydro-2H-pyran-2-one; 5-Hydroxy-2-methylvaleric acid lactone; δ-Hexalactone, 2-methyl-; 2-Methyl-5-pentanolide
EINECS	234-235-8

Quality Control

Our 2-Methyl-5-Hydroxypentanoic Acid Lactone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, and we can support customer-specific validation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Optical Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.