Description

2-(4-Bromophenyl)-1,3-dioxolane is a versatile brominated acetal derivative, primarily serving as a key synthetic intermediate in advanced organic chemistry. Its value lies in the protected aldehyde functionality, which provides chemists with a stable handle for selective transformations under conditions where a free aldehyde would be reactive. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries engaged in multi-step synthesis, particularly for constructing complex aromatic and heterocyclic target molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), especially those containing substituted biphenyl or aromatic ether motifs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where the bromophenyl group is incorporated into the final active molecule.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized phosphine or nitrogen-based ligands used in transition metal catalysis.
• Material Science Research: Employed in the synthesis of monomers for advanced polymers, liquid crystals, or organic electronic materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, or Stille couplings to form carbon-carbon bonds.
• Academic & R&D Laboratories: A valuable reagent for methodological development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	2-(4-Bromophenyl)-1,3-Dioxolane
CAS No.	10602-01-4
Molecular Formula	C9H9BrO2
Molecular Weight	229.07 g/mol
Synonyms	4-Bromobenzaldehyde ethylene acetal; p-Bromobenzaldehyde ethylene acetal; 1,3-Dioxolane, 2-(4-bromophenyl)-; 2-(p-Bromophenyl)-1,3-dioxolane; 4-Bromophenyl-1,3-dioxolane; (4-Bromophenyl)-1,3-dioxolane; Benzaldehyde, 4-bromo-, ethylene acetal
EINECS	Contact for details

Quality Control

Our 2-(4-Bromophenyl)-1,3-dioxolane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.