Description

2-O,3-O,5-O,6-O,7-o-Pentakis(Trimethylsilyl)-D-Glycero-D-Gulo-Heptonic Acid 1,4-Lactone is a highly functionalized, protected sugar lactone derivative, serving as a critical chiral building block and synthetic intermediate. Its value lies in providing a complex, multi-protected carbohydrate scaffold that is essential for the stereoselective synthesis of advanced molecules. This compound is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and complex natural product analogs.

Application

• Pharmaceutical Intermediate: Key chiral precursor for the synthesis of nucleoside analogs, antiviral agents, and other complex therapeutic molecules.
• Carbohydrate Chemistry Research: Serves as a protected heptonic acid lactone for studying glycosylation reactions and synthesizing complex oligosaccharides.
• Agrochemical Synthesis: Used in the development of novel, biologically active compounds with specific stereochemical configurations.
• Glycoconjugate Production: Building block for creating glycopeptides, glycolipids, and other biologically relevant conjugates.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes to study biological recognition and signaling pathways.
• Asymmetric Synthesis: Provides a source of multiple chiral centers for the construction of complex natural products and fine chemicals.

Basic Information

Product Name	2-O,3-O,5-O,6-O,7-o-Pentakis(Trimethylsilyl)-D-Glycero-D-Gulo-Heptonic Acid 1,4-Lactone
CAS No.	10589-41-0
Molecular Formula	C26H58O7Si5
Molecular Weight	627.19 g/mol
Synonyms	Pentakis-O-(trimethylsilyl)-D-glycero-D-gulo-heptono-1,4-lactone; D-glycero-D-gulo-Heptonic acid, 2,3,5,6,7-pentakis-O-(trimethylsilyl)-, 1,4-lactone; 1,4-Lactone of 2,3,5,6,7-Penta-O-trimethylsilyl-D-glycero-D-gulo-heptonic acid; Protected Heptonic Acid Lactone; TMS-protected Sugar Lactone; 10589-41-0; Heptonic acid lactone, pentakis(trimethylsilyl) derivative
EINECS	Contact for details

Quality Control

Our 2-O,3-O,5-O,6-O,7-o-Pentakis(Trimethylsilyl)-D-Glycero-D-Gulo-Heptonic Acid 1,4-Lactone is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and specific optical rotation measurement to ensure identity, strength, and quality. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.