Description

p-Chlorophenyltrimethylsilane is a versatile organosilicon compound featuring a chlorophenyl group, making it a valuable reagent in synthetic organic chemistry. Its primary value lies in its dual functionality, serving as both a protected phenol derivative and a versatile silylating agent for introducing the trimethylsilyl (TMS) group. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for complex synthesis, including the production of liquid crystals and functional polymers.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly where a protected chlorophenol moiety is required.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and pesticides as a precursor for more complex chlorinated aromatic structures.
• Silylating Agent: Employed to introduce the trimethylsilyl group onto alcohols, amines, and other nucleophiles, protecting functional groups during multi-step synthesis.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing chlorinated aromatic components used in liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modification: Acts as a monomer or cross-linking agent in the production of specialty silicones and silicon-containing polymers to enhance thermal stability and chemical resistance.
• Organic Synthesis Reagent: Utilized in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) due to the reactivity of the chloroarene group.

Basic Information

Item	Details
Product Name	p-Chlorophenyltrimethylsilane
CAS No.	10557-71-8
Molecular Formula	C9H13ClSi
Molecular Weight	184.74 g/mol
Synonyms	1-Chloro-4-(trimethylsilyl)benzene; 4-Chlorophenyltrimethylsilane; (4-Chlorophenyl)trimethylsilane; Trimethyl(4-chlorophenyl)silane; p-Chlorophenyltrimethylsilane; 4-Chloro-1-(trimethylsilyl)benzene; (p-Chlorophenyl)trimethylsilane; TMS-Protected 4-Chlorophenol
EINECS	Contact for details

Quality Control

Our p-Chlorophenyltrimethylsilane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.510 - 1.520
Density (20°C)	1.00 - 1.05 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.