Description

(1R,2R)-cis-1-(Chloromethyl)-2-Methylcyclopropane is a high-purity, stereochemically defined cyclopropane derivative, serving as a critical chiral building block in advanced organic synthesis. Its value lies in the unique reactivity and three-dimensional structure of the cyclopropane ring, which is leveraged to construct complex molecular architectures with high precision. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of antiviral, anticancer, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the cyclopropane moiety contributes to biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with tailored properties.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme mechanisms and biological pathways.
• Flavor and Fragrance Industry: Acts as an intermediate for synthesizing complex terpenoid-like aroma compounds.

Basic Information

Product Name	(1R,2R)-cis-1-(Chloromethyl)-2-Methylcyclopropane
CAS No.	10524-04-6
Molecular Formula	C6H11Cl
Molecular Weight	118.60 g/mol
Synonyms	(1R,2R)-1-(Chloromethyl)-2-methylcyclopropane; (1R-cis)-1-(Chloromethyl)-2-methylcyclopropane; cis-1-Chloromethyl-2-methylcyclopropane; (1R,2R)-rel-1-(Chloromethyl)-2-methylcyclopropane; 1-Chloromethyl-2-methylcyclopropane, (1R,2R)-; Cyclopropane, 1-(chloromethyl)-2-methyl-, (1R,2R)-
EINECS	Contact for details

Quality Control

Every batch of (1R,2R)-cis-1-(Chloromethyl)-2-Methylcyclopropane is produced under strict quality management systems. We employ advanced analytical techniques, including chiral HPLC and GC, to ensure excellent enantiomeric excess (ee) and chemical purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your R&D and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.