Description

n-Methyl-2-Adamantanamine Hydrochloride is a high-purity pharmaceutical intermediate and research chemical characterized by its unique adamantane cage structure. This compound is valued for its role in the synthesis of advanced therapeutic agents, particularly within the central nervous system (CNS) drug discovery pipeline. Key industries that utilize this material include pharmaceutical R&D, fine chemical synthesis, and academic research institutions focusing on medicinal chemistry.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel adamantane-based drug candidates, including potential antiviral and neurological therapeutics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new chemical entities with optimized pharmacological profiles.
• Fine Chemical Synthesis: Serves as a precursor for the preparation of more complex, functionalized adamantane derivatives.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Biochemical Tool Compound: Utilized in preclinical research to investigate biological pathways and receptor interactions.

Basic Information

Product Name	n-Methyl-2-Adamantanamine Hydrochloride
CAS No.	10523-69-0
Molecular Formula	C11H20ClN
Molecular Weight	201.74 g/mol
Synonyms	1-Methyl-2-adamantanamine Hydrochloride; 2-(Methylamino)adamantane Hydrochloride; Memantine Impurity; 1-Amino-2-methyladamantane Hydrochloride; NMDA Receptor Antagonist Intermediate; Adamantan-2-yl-methyl-amine Hydrochloride; 2-Methyl-2-aminoadamantane Hydrochloride
EINECS	Contact for details

Quality Control

Our n-Methyl-2-Adamantanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring material of pharmaceutical intermediate grade.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.